What Is 4-Butylphenylboronic Acid CAS 145240-28-4? Properties, Applications, and Sourcing
What Is 4-Butylphenylboronic Acid CAS 145240-28-4? Properties, Applications, and Sourcing
4-Butylphenylboronic acid, CAS 145240-28-4, is an arylboronic acid with a butyl substituent in the para position of its phenyl ring. Its molecular formula is C10H15BO2, and its calculated molar mass is approximately 178.04 g/mol. In organic synthesis, it can serve as an aryl-group building block, including in Suzuki–Miyaura coupling when the substrate, catalyst, and reaction conditions are suitable. For B2B procurement, buyers should confirm the exact chemical identity, agreed quality requirements, documentation, and intended-use fit with the supplier before placing an order.
Key Takeaways
- 4-Butylphenylboronic acid is an aromatic boronic acid identified by CAS 145240-28-4 and formula C10H15BO2.
- Its boronic acid group can participate in carbon–carbon bond-forming chemistry, while the para-butyl substituent remains part of the resulting aryl structure.
- Suitability depends on the target molecule, reaction conditions, material quality, and how the product is stored and handled.
- Before buying, request a current specification and batch-specific documentation, and clarify quantity, packaging, lead time, and shipping requirements.
Identity and Core Function
What the CAS number identifies
CAS 145240-28-4 is the registry identifier used to distinguish this substance from other chemical materials. The name describes a phenylboronic acid carrying a butyl group at the 4-position, also called the para position, relative to the boronic acid substituent. This structural description matters because positional isomers can have different identities and should not be treated as interchangeable. Buyers should match the CAS number and structural name against their internal material record and procurement specification.
How it functions in synthesis
Arylboronic acids are commonly used as coupling partners in palladium-catalyzed Suzuki–Miyaura reactions. In a suitable reaction, the aryl group attached to boron can form a new carbon–carbon bond with an appropriate coupling partner, such as an aryl halide. The 4-butyl substituent is retained as part of the aryl fragment, so the reagent may be considered when a target structure calls for that specific substitution pattern. Reaction performance is not guaranteed by reagent identity alone; catalyst choice, solvent, base, substrate, and process conditions all matter.
The butyl group is a nonpolar alkyl substituent, which can influence the overall physical and chemical behavior of a molecule containing this building block. The actual effect on solubility, reactivity, or product properties depends on the full structure and experimental conditions. We recommend evaluating those properties in the context of the intended synthesis rather than assuming that the substituent will produce a particular outcome.
Properties and Material Considerations
The molecular formula C10H15BO2 and calculated molar mass of approximately 178.04 g/mol provide useful reference points for material identification and quantity planning. For example, 1 mmol corresponds to approximately 178.04 mg on a formula-mass basis; this is a calculated conversion, not a recommended reaction charge. A 10 mmol quantity corresponds to approximately 1.780 g on the same basis, before any allowance for purity, weighing, or handling losses.
Physical appearance, assay, water content, impurity profile, and storage guidance should be taken from the supplier’s current specification and batch documents rather than inferred from the chemical name. Boronic acid materials may be sensitive to storage or handling conditions, and the appropriate controls depend on the supplied grade and packaging. We advise buyers to follow the product-specific safety data sheet (SDS), certificate of analysis (COA), and applicable site procedures.
Applications and Use Scenarios
Organic synthesis and research
The most direct application is as a building block in laboratory or process-development synthesis where a para-butyl-substituted aromatic unit is needed. A chemist may assess it for coupling routes to biaryl or other aryl-containing compounds, provided the chosen partner and conditions are compatible. It may also be evaluated in route screening or intermediate preparation. These are potential synthesis uses, not claims that the compound is suitable for every route or a particular regulated end use.
Intermediate selection and scale-up planning
At the planning stage, teams should check whether the target structure specifically requires the 4-butyl substitution pattern and whether the boronic acid route fits the wider synthesis. For scale-up, the material’s quality profile, handling requirements, and supply continuity become important alongside reaction performance. Buyers should share intended quantity and project stage when requesting a quotation, since sample, development, and production needs can involve different packaging and documentation expectations.
Material Options and Specification Review
When sourcing, distinguish the named boronic acid from related materials such as other positional isomers, protected boronate esters, or boroxine forms. These materials may serve related synthetic roles, but they are not identical products and should not be substituted without technical review. If a process requires a particular form, state that requirement explicitly in the inquiry and purchase specification.
Maison Chemical Product Page
| Specification item | What the buyer should confirm |
|---|---|
| Identity | Product name, CAS 145240-28-4, and the required positional isomer |
| Quality limits | Assay or purity method, acceptance criteria, and relevant impurity requirements |
| Batch documentation | Availability of a batch-specific COA and current SDS |
| Packaging and shipment | Pack size, container type, labeling, and destination-specific shipping requirements |
The table is a purchasing checklist, not a statement of guaranteed product specifications. Buyers should agree acceptance criteria in writing before order confirmation, particularly when analytical methods or impurity thresholds are critical. If a required test method is not listed in the available documentation, ask whether it can be provided or evaluated before making assumptions.
How to Select a Supplier
Assess identity, quality, and documentation
Start by asking the supplier to confirm the product name and CAS number, and compare these details with your approved material record. Review the offered specification for the quality attributes relevant to your process, and check that the COA corresponds to the supplied batch. If your project requires additional analytical information, describe the required method or limit clearly so the supplier can confirm availability before shipment.
Review commercial and logistics fit
Request a quotation that identifies the requested quantity, packaging, delivery destination, and any documentation needs. Confirm the quoted lead time and minimum order quantity directly, because these details can vary with stock status, production planning, packaging, and destination. For international shipments, buyers should also verify import requirements and ensure the shipping paperwork matches their local procedures.
For process-critical projects, consider whether the supplier can communicate changes to product specifications or supply conditions and can respond to technical documentation questions. Avoid relying on broad claims such as “high purity” without a defined specification and supporting batch information. A clear written agreement reduces ambiguity between the purchase order, the product supplied, and the material your technical team has approved.
Maison Chemical Supplier Support
At Maison Chemical, we support B2B inquiries for 4-Butylphenylboronic acid CAS 145240-28-4 by helping buyers clarify product identity, requested quality parameters, quantity, packaging, and destination. We can discuss the documentation available for the offered batch and confirm commercial details during quotation. Availability, specifications, minimum order quantity, and lead time should be confirmed for each inquiry rather than assumed from a general product description.
To help us respond efficiently, include your target quantity, required specification or assay range, intended packaging, destination country, and any documentation or analytical requirements. If you are comparing this material with a boronate ester or another positional isomer, identify the alternative clearly so the inquiry can be reviewed against your technical need. Final use and process suitability should be assessed by your qualified technical team.
Conclusion
4-Butylphenylboronic acid CAS 145240-28-4 is a para-butyl-substituted arylboronic acid with formula C10H15BO2 and calculated molar mass of approximately 178.04 g/mol. Its core value is as a potential aryl building block in appropriate organic synthesis, including compatible Suzuki–Miyaura coupling routes. The right buying decision depends on confirming the exact material form, quality requirements, documentation, and supply terms for your project.
As a next step, prepare a purchase inquiry with your required quantity, specification, packaging, destination, and documentation needs. Contact Maison Chemical to discuss a quotation and confirm current batch and delivery details before placing an order.
Are you interested in learning more about 4-Butylphenylboronic acid CAS 145240-28-4? Contact us today to secure an expert consultation!